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For example, vaping can sometimes cause E-cigarette- or Vaping Product-Associated Lung Injury (EVALI), according to a 2020 review published by The American Journal of Medicine
[53] High amounts of vapor particle deposition are believed to enter into the lungs with each puff because the particle size in e-cigarette vapors is within the respiratory range
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These data demonstrate that flavor chemicals are a major component of currently marketed EC refill fluids and their health effects on EC users should be addressed